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Kappa light chain Illustration and Icon
Kappa light chain
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A simplified schematic depicts the immunoglobulin kappa light chain (Igκ), a polypeptide subunit of an antibody (immunoglobulin, Ig) within the adaptive immune system. In biological hierarchy, it is a protein chain within the immunoglobulin macromolecule on B-cell receptors (BCR, B-cell receptor) and in secreted antibodies circulating in blood and lymph. In immunology and biochemistry, it contributes to antigen binding through variable (V) and constant (C) domains and supports humoral immunity.
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