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Jennifer doudna emmanuelle charpentier nobel crispr molecule model Illustration and Icon
Jennifer doudna emmanuelle charpentier nobel crispr molecule model
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Illustration of two adult humans presenting a molecular model of the CRISPR (clustered regularly interspaced short palindromic repeats)âCas9 complex bound to DNA. The image depicts a ribonucleoprotein (RNP) composed of CRISPR-associated protein 9 (Cas9) and guide RNA (gRNA) engaging double-stranded DNA (dsDNA), a lower-level component within the cellular genome. Relevant fields are genetics, molecular biology, and biochemistry. Functionally, the complex enables sequence-specific genome editing by introducing targeted double-strand breaks. The human subjects (Homo sapiens) are shown holding the macromolecular model.
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