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Ion channel linked receptor inactive Illustration and Icon
Ion channel linked receptor inactive
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Stylized diagram of a ligand-gated ion channel receptor in its inactive, closed state. The receptor is a transmembrane protein complex embedded in the cell plasma membrane, illustrating a protein within a cellular membrane hierarchy. In cell biology and physiology/neurobiology, ionotropic receptors (LGIC, ligand-gated ion channel) open upon ligand binding; here the pore is closed, preventing ion flux (e.g., Na+, K+, Ca2+, or Cl?). Functionally, the closed conformation preserves membrane potential and delays rapid signaling until activation.
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