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Intrathecal injection mice 2 Illustration and Icon

Intrathecal injection mice 2

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A gloved hand inserts a fine needle connected to tubing and a syringe into the lower lumbar region of a laboratory mouse, exposing skeletal and central nervous system anatomy. The procedure illustrates intrathecal (IT) delivery into the subarachnoid space to access cerebrospinal fluid (CSF) surrounding the spinal cord within the vertebral canal, part of the central nervous system (CNS). In laboratory animal science and neuropharmacology, this technique in Mus musculus (house mouse) enables direct CNS administration of analgesics, anesthetics, dyes, or experimental therapeutics.

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