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Intimal calcification Illustration and Icon
Intimal calcification
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A schematic cross-section of an artery depicts pathologic mineral deposition within the tunica intima. The image shows a calcified plaque (intimal calcification, IC) located just beneath the endothelial surface and encircled by spindle-shaped vascular smooth muscle cells in the tunica media. In the biological hierarchy, the calcified lesion resides within the arterial wall of the cardiovascular system. In cardiovascular pathology and histology, this lesion stiffens the vessel and reduces compliance, potentially contributing to luminal compromise.
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