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Intermediate Filaments Cardiac Muscle Zoom Illustration and Icon

Intermediate Filaments Cardiac Muscle Zoom

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A schematic microanatomical view of a cardiomyocyte shows intermediate filaments encircling a myofibril and connecting to the sarcolemma and the nuclear envelope. Within the biological hierarchy, this cell type resides in cardiac muscle tissue of the heart, part of the cardiovascular system. The depicted elements are cytoskeletal protein polymers classified as intermediate filaments (IF), primarily desmin (DES), which link Z-discs (Z-line), align myofibrils, and mechanically couple the contractile apparatus to cell–cell junctions and the nucleus, thereby maintaining structural integrity and aiding force transmission during contraction.

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