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Integrin receptor Illustration and Icon
Integrin receptor
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Stylized depiction of a cell-surface heterodimeric receptor composed of two elongated subunits, representing an integrin. The structure is a transmembrane protein complex (type: receptor) with integrin alpha (ITGA) and integrin beta (ITGB) chains embedded in the plasma membrane of a eukaryotic cell, illustrating a hierarchy of subunit within receptor within cell. In cell biology and biochemistry, this receptor binds extracellular matrix (ECM, extracellular matrix) components to mediate cell adhesion and mechanotransduction, enabling bidirectional signaling (inside-out and outside-in) and linkage to the actin cytoskeleton.
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