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Immunoglobulin molecule Illustration and Icon
Immunoglobulin molecule
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A schematic diagram depicts the Y‑shaped architecture of an antibody. It shows an immunoglobulin (Ig) protein of the adaptive immune system composed of two identical heavy chains and two identical light chains linked by disulfide bonds at the hinge. Each arm contains variable domains (VH, variable heavy; VL, variable light) and constant domains (CH1, constant heavy 1; CL, constant light) that form the antigen-binding Fab fragments, while the stem comprises CH2 and CH3 domains constituting the Fc region. In immunology and protein biochemistry, this glycoprotein mediates antigen recognition, neutralization, opsonization, and complement activation.
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