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Immunoglobulin hclgg chang Illustration and Icon
Immunoglobulin hclgg chang
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A schematic illustration of an antibody (immunoglobulin G, IgG) depicting a Y-shaped protein with two antigen-binding Fab (fragment antigen-binding) arms and a dimeric Fc (fragment crystallizable) region. The constant heavy chain (CH) domains are labeled CH2 and CH3, indicating subdomains within the Fc of the IgG molecule, a glycoprotein of the adaptive immune system. In immunology and biochemistry, the Fc mediates effector functions such as complement activation and Fc receptor interactions, while the Fab regions bind antigen; the soluble protein circulates in blood plasma and interstitial fluid.
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