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Hypothalamic nuclei mouse brain shape front Illustration and Icon

Hypothalamic nuclei mouse brain shape front

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A coronal schematic of the mouse brain depicts paired hypothalamic nuclei highlighted at the ventral midline. These neuronal cell groups (nuclei) lie within the hypothalamus of the diencephalon, an organ-level region of the central nervous system (CNS) in Mus musculus (house mouse). In neuroanatomy and physiology, the hypothalamic nuclei coordinate homeostatic functions, driving neuroendocrine outputs via the pituitary and modulating autonomic activity, feeding, thermoregulation, and circadian rhythms, including regulation of the hypothalamic–pituitary–adrenal (HPA) axis.

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