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Hydrogel forming microneedles tissue 3 Illustration and Icon
Hydrogel forming microneedles tissue 3
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A schematic depicts a hydrogel-forming microneedle (HMN) array penetrating skin. Dry polymer microneedles (MN) cross the stratum corneum (SC) into viable tissue and swell into a hydrogel network upon contact with interstitial fluid (ISF). In the structural hierarchy, the device interfaces with the epidermis and dermis of the integumentary system. Dots represent diffusion of drug molecules from a reservoir in the patch backing into tissue and selective uptake of biomarkers from ISF. This medical device supports transdermal delivery and minimally invasive diagnostics in biomedical engineering, materials science, and dermatology.
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