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Hydrogel forming microneedles tissue 1 Illustration and Icon
Hydrogel forming microneedles tissue 1
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A schematic cross-section illustrates a hydrogel-forming microneedle (HF-MN) array penetrating skin tissue. Blue conical microneedles traverse the stratum corneum (SC) into underlying epidermal/dermal layers of the integumentary system, while a red backing layer with dispersed payload rests above the surface. In anatomy, physiology, and pharmaceutics, this microfabricated device (MN) enables transdermal delivery and sampling by swelling upon interstitial fluid uptake. Hierarchically, the MN device interfaces with cutaneous tissue layers to bypass the SC barrier and enhance percutaneous transport.
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