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Heart second harmonic generation imaging 2 Illustration and Icon
Heart second harmonic generation imaging 2
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A nonlinear optical microscopy image using second harmonic generation (SHG) shows a cross-sectional view of the heart, with the myocardial wall rendered as a red signal surrounding chamber-like luminal spaces on a dark background. The scene depicts cardiac muscle tissue (myocardium; tissue) within the heart (organ) of the cardiovascular system. In anatomy and histology, SHG enables label-free visualization of non-centrosymmetric structures, commonly fibrillar collagen and myofibrillar organization, supporting applications in cardiac physiology and pathology for assessing extracellular matrix (ECM) and structural integrity.
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