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Heart second harmonic generation imaging 1 Illustration and Icon

Heart second harmonic generation imaging 1

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A false-color biomedical visualization depicts cardiac tissue captured by second harmonic generation (SHG) microscopy. The image represents the heart, an organ within the cardiovascular system, emphasizing the myocardium (tissue) where intrinsic noncentrosymmetric proteins generate label-free contrast. In biophotonics and cardiac histology, SHG highlights fibrillar collagen within the extracellular matrix (ECM) and myosin within cardiomyocytes, enabling assessment of fiber orientation and fibrosis remodeling for physiological and pathology studies.

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