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Healthy substantia nigra Illustration and Icon
Healthy substantia nigra
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Healthy substantia nigra. This stylized cross-sectional view of the midbrain shows the substantia nigra (SN) as paired, darkly pigmented arcs indicating intact neuromelanin. In the biological hierarchy, the SN is a brain nucleus within the ventral midbrain of the central nervous system (CNS). In neuroanatomy and neurophysiology, its dopaminergic neurons synthesize dopamine (DA) and modulate basal ganglia circuits, supporting motor control; neuropathology links degeneration here to parkinsonism.
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