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Growth factor receptor front Illustration and Icon
Growth factor receptor front
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Growth factor receptor front. This schematic depicts a dimeric transmembrane receptor protein in frontal view, with three extracellular ligand-binding modules, two single-pass transmembrane segments, and paired cytoplasmic kinase domains represented as rectangles. In the biological hierarchy, it is a membrane protein embedded in the plasma membrane of a cell. In cell biology and biochemistry, an RTK (receptor tyrosine kinase) binds growth factors to promote dimerization, autophosphorylation, and signal transduction pathways that regulate proliferation, survival, and differentiation.
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