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gprotein-linked-receptor-active

Gprotein linked receptor active Illustration and Icon

Gprotein linked receptor active

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A stylized diagram depicts an activated G protein–coupled receptor (GPCR) with its associated heterotrimeric G protein at the plasma membrane. The seven-transmembrane receptor protein (type: membrane receptor) resides within the cell surface, representing a protein complex within a cellular membrane hierarchy. In cell biology and biochemistry, activation of the GPCR triggers GDP–GTP exchange on the Gα (alpha) subunit, initiating intracellular signal transduction and second‑messenger pathways. The site is the plasma membrane of a eukaryotic cell; species is not specified.

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