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Goblet cells in simple columnar epithelium Illustration and Icon

Goblet cells in simple columnar epithelium

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An illustration depicts a single layer of simple columnar epithelium with interspersed goblet cells. The tissue (SCE, simple columnar epithelium) comprises tall epithelial cells with basally located oval nuclei, while goblet cells (GCs) display apical mucin granules. In histology and physiology, this epithelial tissue lines mucosal surfaces, where GCs secrete mucins that form mucus, providing lubrication and barrier protection at the lumen. The hierarchy shown is secretory cells embedded within an epithelial tissue forming the lining of a mucosa.

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