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G protein Illustration and Icon
G protein
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A stylized molecular schematic depicts a guanine nucleotidebinding protein that mediates signal transduction downstream of a G proteincoupled receptor (GPCR) on the cytoplasmic face of the plasma membrane. In biological hierarchy, it is a protein molecule operating within a cellular signaling pathway. In biochemistry and physiology, it cycles between GDP (guanosine diphosphate) and GTP (guanosine triphosphate) states to regulate downstream effectors, enabling amplification of extracellular cues into intracellular responses.
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