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Fc immunoglobulin element Illustration and Icon
Fc immunoglobulin element
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A schematic diagram of the antibody fragment crystallizable (Fc) region shows two paired constant heavy-chain domains: CH2 linked to CH3 on each heavy chain, with an interchain connection between the CH2 domains. In immunology and structural biochemistry, this protein domain complex resides within the constant region of immunoglobulins (Ig) and mediates effector functions by engaging Fc receptors (FcRs) and complement component 1q (C1q). The illustration represents protein domains within an antibody molecule of the humoral immune system, located extracellularly in serum.
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