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extracellular-environment

Extracellular environment Illustration and Icon

Extracellular environment

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Illustration of a cell surface with a lipid bilayer and transmembrane proteins beneath an intricate glycocalyx. At a hierarchical level, macromolecules compose the extracellular matrix (ECM) surrounding the plasma membrane (PM) of a cell within tissue. In cell biology and glycobiology, proteoglycans bearing glycosaminoglycan (GAG) chains and membrane glycoproteins mediate structural support, hydration, adhesion, and receptor-mediated signaling. The entities shown are molecules and macromolecular complexes located in the extracellular space at the cell membrane.

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