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Epidermis dermis Illustration and Icon
Epidermis dermis
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Cross-sectional histology diagram of skin showing a stratified squamous keratinized epithelium over connective tissue at the body surface. The epidermis comprises the stratum corneum (SC), granular, spinous, and basal layers of keratinocytes resting on the basement membrane (BM), which overlies the dermis rich in extracellular matrix (ECM). Within the integumentary system hierarchy, these tissues together form the organ-level skin. In histology and dermatology, this arrangement provides a barrier to microbes, ultraviolet radiation, and transepidermal water loss, while the dermis supplies structural support, innervation, and vascular anchorage.
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