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enzyme-linked-receptor-inactive-2

Enzyme linked receptor inactive 2 Illustration and Icon

Enzyme linked receptor inactive 2

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A simplified schematic shows an enzyme?linked cell?surface receptor in an inactive state. Two light?blue single?pass transmembrane receptor monomers are depicted separately, each with an extracellular domain and a cytoplasmic tail, suggesting the absence of ligand?induced dimerization and catalytic activation. The icon represents the membrane?spanning topology typical of receptor tyrosine kinases and related signaling proteins, emphasizing their role in signal transduction only upon ligand binding and receptor clustering.

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