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Enzyme linked receptor inactive 1 Illustration and Icon
Enzyme linked receptor inactive 1
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A simplified schematic depicts two separate enzyme?linked receptors spanning the plasma membrane in an inactive, unliganded state. Each receptor is a transmembrane protein with an extracellular ligand?binding region and a cytoplasmic catalytic domain illustrated as a globular enzyme. In the biological hierarchy, the element is a membrane protein embedded within the cells plasma membrane. In cell biology and biochemistry, such receptors (e.g., RTK, receptor tyrosine kinase) enable signal transduction via ligand?induced dimerization and autophosphorylation, which is not occurring in this inactive depiction.
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