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egfr-receptor

Egfr Receptor Illustration and Icon

Egfr Receptor

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Schematic of the epidermal growth factor receptor (EGFR/ERBB1, also known as HER1) shown as a ligand-bound homodimer at the plasma membrane. The figure highlights the extracellular ligand-binding regions (with yellow EGF ligands), single-pass transmembrane helices, and the cytoplasmic tyrosine kinase domains poised for autophosphorylation. Color coding emphasizes the receptor chains in purple with green subdomains and light blue dimer interface, conveying activation by ligand-induced dimerization and downstream signaling initiation.

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