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Dystrophic microglia engulfing synapses Illustration and Icon
Dystrophic microglia engulfing synapses
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A stylized diagram shows an irregularly branched microglial cell contacting a dendritic segment with multiple spine synapses, with a microglial process enclosing a synaptic bouton. In the biological hierarchy, a glial immune cell functions within CNS (central nervous system) neural tissue to phagocytose synaptic elements of neurons. The image illustrates cellular mechanisms of synaptic pruning and debris clearance studied in neuroanatomy, neuroimmunology, and neuropathology, emphasizing dystrophic microglial morphology during synaptic engulfment and the formation of intracellular phagocytic compartments.
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