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Dna recombination repeats 2 Illustration and Icon
Dna recombination repeats 2
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A schematic shows intramolecular homologous recombination (HR) between direct repeats (DR) in a DNA molecule, with a crossover represented by an X marking a Holliday junction (HJ). Identical repeat tracts flank an intervening sequence that is excised, forming a circular product and a shortened DNA segment. In molecular genetics, this mechanism restructures genomic DNA and is leveraged in genome engineering for targeted deletion of chromosomal or plasmid segments.
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