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Dna Pipa Distortion 2 Illustration and Icon
Dna Pipa Distortion 2
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Vertical depiction of a DNA double helix with colored base pairs and tan–yellow backbones. A purple pyrrole–imidazole polyamide (PIP/PIPA) resides in the minor groove, inducing local backbone distortion (shown as orange wavy bands) and bending of the duplex. The figure emphasizes sequence-specific minor-groove binding by small-molecule polyamides and the resulting DNA deformation relevant to chemical biology, structural biology, biophysics, genetics, and genomics.
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