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dna-homologous-recombination-2

Dna homologous recombination 2 Illustration and Icon

Dna homologous recombination 2

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Schematic of homologous recombination depicting repair of a DNA double‑strand break. A 3′ single‑stranded tail from the broken chromosomal DNA invades a homologous duplex, forming a displacement loop (D‑loop) and heteroduplex DNA, followed by DNA polymerase–mediated repair synthesis. The illustration shows double‑stranded DNA (dsDNA) helices and a branch linking donor and recipient strands, representing a Holliday junction (HJ) intermediate. In the biological hierarchy, DNA is a nucleic acid molecule within chromosomes of cells, studied in molecular genetics and biochemistry, enabling genome stability and largely error‑free repair.

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