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Dna double helix damage 4 Illustration and Icon
Dna double helix damage 4
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A stylized depiction of a DNA double-strand break shows an orange double helix with fragmented base pairs, representing damage to deoxyribonucleic acid (DNA). The molecule is presented as chromosomal DNA within the cellular genome, illustrating a hierarchy from biopolymer to chromosome. In molecular biology and genetics, such damage, termed a DSB (double-strand break), disrupts genetic information storage and triggers DNA repair pathways, including NHEJ (non-homologous end joining) and HR (homologous recombination), which restore sequence integrity and maintain genome stability.
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