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dna-crispr-cas

Dna crispr cas Illustration and Icon

Dna crispr cas

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A schematic depicts a CRISPR (clustered regularly interspaced short palindromic repeats)–Cas complex bound to double‑stranded DNA, with a guide RNA hybridized to a complementary target sequence inside the nuclease. In molecular biology and genetics, this protein–nucleic acid assembly (Cas, CRISPR-associated nuclease) uses gRNA (guide RNA) to confer sequence specificity and catalyze endonucleolytic cleavage for genome editing. The entities shown are molecules—protein, RNA, and DNA—situated within the cellular genomic hierarchy.

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