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Dihydrotestosterone Illustration and Icon
Dihydrotestosterone
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Diagram of the steroid hormone dihydrotestosterone (DHT) showing its four-ring androgen backbone with a 3-keto group and a 17β-hydroxyl side chain. In biological hierarchy, this small molecule functions within the endocrine system at the cellular level by binding the androgen receptor (AR) to regulate gene expression. In biochemistry and endocrinology, DHT is produced from testosterone by 5α-reductase and acts in peripheral tissues such as prostate, skin, and hair follicles to drive androgen-dependent development and function.
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