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Diffuse axonal injury post trauma condition Illustration and Icon

Diffuse axonal injury post trauma condition

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A schematic shows a neuron with a disrupted axon and torn ends consistent with diffuse axonal injury (DAI). The neuron (cell level) is depicted within central nervous system (CNS) white matter (tissue level). In neuroanatomy and neuropathology, DAI results from rotational acceleration, causing axolemmal rupture and myelin shearing, which impairs action potential conduction and synaptic transmission at the axon terminal.

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