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deletion

Deletion Illustration and Icon

Deletion

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A schematic in cytogenetics illustrating a chromosomal deletion: a banded eukaryotic chromosome loses a contiguous segment, producing a shorter derivative chromosome. At the hierarchy level, genes reside within the chromosome, which is housed in the cell nucleus. The entity shown is a chromosome composed of DNA (deoxyribonucleic acid), representing a structural variant and CNV (copy number variation) that reduces gene dosage. This concept is used in genetics, pathology, and genomics to explain inherited or somatic mutations.

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