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Cytokine receptor perspective Illustration and Icon
Cytokine receptor perspective
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A simplified schematic depicts a dimeric cytokine receptor composed of two parallel subunits, each bearing two oval extracellular (EC) ligand-binding domains atop a single transmembrane (TM) segment. In biological hierarchy, this protein complex resides in the plasma membrane of a eukaryotic cell within the immune signaling system. In immunology and cell biology, such cell-surface receptors bind cytokines to trigger intracellular signal transduction that regulates cell proliferation, differentiation, and survival. The entity illustrated is a membrane receptor protein located on the plasma membrane; species is not specified.
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