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Cytokine receptor il4 structure Illustration and Icon
Cytokine receptor il4 structure
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A simplified structural diagram of the interleukin-4 receptor (IL4R), a type I cytokine receptor protein located on the cell surface. The drawing depicts the extracellular ectodomain as a series of tandem modules, consistent with fibronectin type III–like domains that compose the cytokine-binding region. Within the hierarchy, this membrane protein functions at the cell membrane of the immune system, where in immunology and structural biology it binds IL-4 (interleukin-4) to activate JAK-STAT signaling and drive Th2-associated responses.
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