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Cytokine receptor ifn gamma structure2 Illustration and Icon
Cytokine receptor ifn gamma structure2
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A stylized structural diagram depicts the interferon-gamma receptor as color-coded cylindrical alpha-helices representing transmembrane segments of a multi-subunit complex. In the biological hierarchy, this transmembrane protein complex resides in the plasma membrane of a cell within the immune system. In structural biology and immunology, the receptor (IFNGR; interferon-gamma receptor) binds IFN-γ (interferon gamma) to trigger JAK-STAT (Janus kinase–signal transducer and activator of transcription) signaling, predominantly activating STAT1, thereby promoting antimicrobial and inflammatory gene expression.
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