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cytokine-receptor-ifn-beta-structure

Cytokine receptor ifn beta structure Illustration and Icon

Cytokine receptor ifn beta structure

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A stylized structural illustration depicts the extracellular domains of a cytokine receptor for interferon beta (IFN-β), shown as two color-coded polypeptide chains with repeating motifs representing the heterodimeric interferon alpha/beta receptor (IFNAR1/IFNAR2). In biological hierarchy, these protein subunits form a cell-surface receptor within the immune system. In structural biology and immunology, this receptor-ligand complex enables cytokine binding at the plasma membrane, initiating JAK-STAT signaling (Janus kinase–Signal Transducer and Activator of Transcription) to regulate antiviral and immunomodulatory gene expression.

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