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Cyclic adenosine monophosphate molecule Illustration and Icon
Cyclic adenosine monophosphate molecule
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A stylized chemical structure diagram depicts the nucleotide second messenger cAMP (cyclic adenosine monophosphate). In biological hierarchy, it is a small signaling molecule within the cytosol of cells, part of intracellular signal transduction. The nucleotide comprises an adenine base linked to ribose whose 3′ and 5′ hydroxyls form a cyclic phosphate ester. In biochemistry and physiology, cAMP is generated from ATP (adenosine triphosphate) by adenylate cyclase (ADCY) and activates PKA (protein kinase A) to modulate metabolism and gene regulation.
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