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Crispr cas chimeric Illustration and Icon
Crispr cas chimeric
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A schematic illustrates a CRISPR–Cas genome editing reaction in which a Cas endonuclease is directed by a chimeric single‑guide RNA (sgRNA; fusion of CRISPR RNA and trans‑activating CRISPR RNA) to a complementary DNA sequence, producing double‑strand breaks indicated by scissors icons. In the biological hierarchy, a specific gene locus within chromosomal DNA is targeted by a protein–RNA complex. In molecular biology and genetics, this system enables targeted mutagenesis and gene knockout. The depicted entity types are nucleic acids (DNA, RNA) and a CRISPR‑associated (Cas) protein.
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