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Coagulation front cut Illustration and Icon

Coagulation front cut

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Coagulation front cut. This schematic shows a blood vessel lumen with a developing intravascular thrombus at the narrowed end and flowing blood proximally. The illustration, relevant to hematology, vascular physiology, and pathology, depicts a fibrin mesh stabilizing aggregated platelets to form a clot, trapping erythrocytes (RBCs) and leukocytes (WBCs) with lobulated nuclei. At a higher level of organization, the thrombus is a structure within a vessel of the cardiovascular system. The depicted elements are cells and proteins whose application is hemostasis but, when intraluminal, can obstruct perfusion and cause thrombosis.

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