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Ch3 immunoglobulin element Illustration and Icon
Ch3 immunoglobulin element
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A simple schematic label highlights the CH3 (constant heavy chain 3) domain of an immunoglobulin (Ig) molecule, represented as an orange rounded rectangle. In the biological hierarchy, this protein domain resides within the Fc (fragment crystallizable) region of the antibody heavy chain, a component of the adaptive immune system. In immunology and structural biology, the CH3 domain contributes to heavy-chain dimerization and stability and participates in FcRn (neonatal Fc receptor) interactions at the CH2–CH3 interface. The entity shown is a protein domain, not a whole molecule.
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