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ch2-immunoglobulin-element

Ch2 immunoglobulin element Illustration and Icon

Ch2 immunoglobulin element

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A schematic icon shows an orange rounded rectangle labeled CH2, representing the constant heavy chain domain 2 (CH2) of an immunoglobulin (Ig). In protein hierarchy, this is a domain within the heavy chain that resides in the fragment crystallizable (Fc) region of an antibody, typically positioned between CH1 and CH3. In immunology and structural biology, the CH2 domain contributes to Fc-mediated effector functions, enabling complement activation and Fc receptor interactions essential for antibody-mediated immune responses.

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