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Calcium sensing receptor 1 Illustration and Icon
Calcium sensing receptor 1
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A stylized schematic depicts the calcium‑sensing receptor (CaSR), illustrating a multi‑pass membrane protein embedded in a cell’s plasma membrane. Multiple transmembrane α‑helices connected by extracellular and cytoplasmic loops indicate a class C G protein–coupled receptor (GPCR). In cell biology and physiology, CaSR detects changes in extracellular Ca2+ concentration and initiates GPCR signaling to regulate calcium homeostasis and hormone secretion. Hierarchically, it represents a protein within the plasma membrane of a cell at the tissue interface.
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