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Bone growth zones resting proliferation hypertrophic Illustration and Icon
Bone growth zones resting proliferation hypertrophic
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A schematic cross-section of a long bone illustrates the epiphyseal growth plate with distinct cartilage zones. The image depicts chondrocytes (cells) within hyaline cartilage (tissue) organized into a resting zone, a proliferative zone with columnar cell stacks, and a hypertrophic zone with enlarged lacunae, located at the metaphysis between epiphysis and diaphysis. In anatomy and histology, this physis (growth plate) drives longitudinal bone elongation via endochondral ossification (EO), as chondrocytes secrete extracellular matrix (ECM) that mineralizes and is replaced by trabecular bone.
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