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Blood vessel 1 Illustration and Icon

Blood vessel 1

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A simplified cross-sectional diagram of a blood vessel wall shows three concentric layers. From the lumen outward appear the tunica intima (TI) with a single layer of endothelial cells, the tunica media (TM) composed of smooth muscle cells (SMCs), and the tunica adventitia (TA) of connective tissue and extracellular matrix (ECM). In the biological hierarchy, endothelial and smooth muscle cells form tissues that build the vascular wall within the cardiovascular system. In anatomy, histology, and physiology, this structure conducts blood and regulates vascular tone, flow, and hemodynamic pressure within the circulatory network.

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