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Blood brain vessel disrupted barrier cut Illustration and Icon
Blood brain vessel disrupted barrier cut
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A schematic of a cerebral microvessel illustrates a disrupted blood–brain barrier (BBB) within the central nervous system (CNS). The capillary endothelium with tight junctions is breached, allowing leukocytes to transmigrate and plasma components to leak from the lumen containing erythrocytes. Perivascular neurons and glial cells, including astrocytic endfeet, border the vessel, representing the neurovascular unit hierarchy. In neuroanatomy and neuropathology, this anatomical barrier regulates molecular trafficking and protects neural tissue.
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