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Blood brain barrier cut Illustration and Icon
Blood brain barrier cut
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A cross-sectional illustration of a brain capillary shows a red blood cell in the lumen, surrounded by endothelial cells sealed by tight junctions, a basal lamina, and enveloping astrocyte endfeet that together constitute the blood–brain barrier (BBB). In neuroanatomy, histology, and physiology, this cellular–tissue hierarchy represents endothelial cells within a microvessel of the central nervous system (CNS). Functionally, the BBB restricts paracellular diffusion, supports selective carrier-mediated transport, and maintains ionic and metabolic homeostasis essential for neuronal function.
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