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Blood Brain Barrier Breakdown Zoom Illustration and Icon
Blood Brain Barrier Breakdown Zoom
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A schematic cross-section of a cerebral microvessel depicts the BBB (blood–brain barrier) with luminal endothelial cells, an abluminal pericyte, and enveloping astrocyte endfeet within the CNS (central nervous system). Black particulates passing from the lumen into the surrounding parenchyma indicate barrier disruption and increased permeability. The illustration highlights the hierarchical organization of capillary endothelium within brain tissue and its role in neurophysiology and neuropathology, where the BBB normally restricts solute and pathogen entry but failure enables neuroinflammatory and toxic infiltration.
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