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Atrial functional mitral regurgitation heart failure preserved ejection fraction Illustration and Icon

Atrial functional mitral regurgitation heart failure preserved ejection fraction

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A cross-sectional schematic of the human heart depicts the left atrium, left ventricle, and the mitral valve within the cardiovascular system. In cardiology and anatomy, the mitral valve (MV) is shown between the LA (left atrium) and LV (left ventricle), illustrating the site implicated in mitral regurgitation (MR), particularly in heart failure with preserved ejection fraction (HFpEF). The organ is located in the thoracic mediastinum of Homo sapiens (human). Functionally, the MV permits diastolic inflow and prevents systolic backflow; MR represents failure of this mechanism with retrograde flow into the LA.

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